Women subjected to depression is one of the most prevailing causes among psychiatric diseases. There is a relation between social support and depression in whose predisposing factors are genetic, psychological, biological, environmental, and hormonal 
. Our main focus of this review is to understand the genes and factors contributing to depression in women. We used PubMed and google search and finally concluded based on 19 papers extending back to the last five years and human species using Mesh terms. Among women with recently diagnosed with cancer and depression, the women must be given the benefit for genetic counseling and must be directly evaluated for current research intervention to reduce risk factors in women.