Self-esteem is essential to our ability to function in a health way. Without the foundation of a solid sense of self-worth we will unable to take the risks and make the decisions necessary to lead a fulfilling and productive life. Adolescence is a period of change- both physical and psychological- and also a time when they form a concept of their own identities in which family and peer interactions play a crucial role. Some adolescents do not receive the individual attention and love from both parents that others of their age receive. Some are left to fend on their own, whereas others are packed off to live with relatives or placed in institutions. The aim of the study is to compare the self-esteem among male and female children at an orphanage home and to associate the level of self-esteem among male children and to associate the level of self-esteem among female children. A comparative study was chosen to assess the self-esteem among male and female orphan children. The present was conducted at Tirunelveli with a sample size of 30 male and female children who met the inclusion criteria were selected by purposive sampling technique. The data was collected by using demographic variables and the self-esteem was assessed by using Rosenberg’s self-esteem scale. The result revealed that Boys had higher self-esteem when compared to girls. The Girls had low self-esteem.